Mrc clinical trials unit address

But unfortunately, when doctors talk about the 'progress of a disease' they mean it has got worse, so it is not good news. Eligibility Criteria.

These are clearly-defined criteria of who is eligible to take part in a study and who is not as given by the inclusion criteria and exclusion criteria of the study.

Epidemiological Study. An epidemiological, or observational, study examines data on individuals with a specific condition and does not intervene in their care, as a clinical trial would. Epidemiological studies examine the effect of certain exposures e.

Ethics Committee. An ethics committee is a committee made up of healthcare professionals and lay people who review funded studies in order to ensure that they are conducted to appropriate ethical standards.

Study participants cannot be approached about joining a clinical study until it has been approved by an ethics committee. Event Rate. The event rate describes the number of people who experience a particular event or outcome measure e.

Evidence Base. A collection of the best available scientific research currently available about a health condition. This is used to make decisions about how best to treat and provide care for individuals with that condition, or to prevent it. Exclusion Criteria. These determine who is not eligible for a clinical study. For example, many trials exclude women who are pregnant, or who may become pregnant, to avoid any possible danger to a baby, or people who are taking a drug that might interact with the treatment being studied.

See also eligibility criteria and inclusion criteria. This is an international quality standard for the conduct of clinical studies. Health Economics. In some clinical trials the cost of all aspects of the treatments being compared is examined. This is particularly important when there is more than one effective approach to treating a condition. Inclusion Criteria. These clearly indicate who can join a trial, e. See also eligibility criteria and exclusion criteria. IPD Meta-analysis.

Individual participant data IPD meta-analyses tend to use standard systematic review and meta-analysis methods, but also involve the central collection and analysis of the original data from all the relevant trials worldwide, rather than just the published summary statistics. Informed Consent. This refers to a participant in a research study agreeing to take part of their own free will after being given all the important facts about that study, and after they have had the chance to ask questions and have them satisfactorily answered and understood.

Interim Analysis. An intervention is a measure which is introduced and evaluated through a clinical trial with the aim of improving health. As a publicly-funded organisation, we have to ensure that it is in the public interest when we use personally-identifiable information from people who have agreed to take part in research.

This means that when you agree to take part in a research study, we will use your data in the ways needed to conduct and analyse the research study. Annual Reports.

More Info. All Vacancies. EQAP Workshop. Leading health research in West Africa to save lives and improve health across the world. This platform will bring in data from multiple different sources, and make the new combined dataset available to researchers. Innovative clinical trial design and meta-analysis extending beyond the boundaries of single cancer types. We look forward to working with the s…. COVID Our primary concern is the safety of all our study participants and minimising any additional strain on our clinical sites and staff.